South China Sea Institute of Oceanology Chinese Academy of Sciences

Revealing Enzymatic Mechanism for Xanthone Formation in Marine Actinomycetes

A research group from the South China Sea Institute of Oceanology of the Chinese Academy of Sciences has revealed the enzymatic mechanism for xanthone formation in actinomycetes .And a broad substrate binding cavity in the resolved crystal structure of FlsO1 explained the functional promiscuity of FlsO1 .This study provides biochemical evidence to support the physiological function of FlsO1 and reveals its underlying mechanism and structure base for the multistep of oxidations .Contact : Prof . ZHANG Changsheng , czhang @ scsio . ac . cn.

ZHANG Changsheng

ZHANG Changsheng , born in Hubei Province 1972 , is the deputy director of South China Sea Institute of Oceanology ( SCSIO ) , Chinese Academy of Sciences ( CAS ) .Dr . ZHANG has published more than 80 publications in SCI journals including Science 、 Nat Chem Biol 、 Nat Commun 、 Mol Cell 、 J Am Chem Soc 、 Angew Chem 、 Chem Sci and is the author and co-author of five books .Dr . ZHANG sits on editorial board for several international periodicals including the top-tier journal Natural Product Reports .

Zhang Si

Researcher of Nanhai Institute of Oceanography, Chinese Academy of Sciences, doctoral supervisor, academician of Chinese Academy of Engineering, academic leader of marine ecological engineering. Focusing on the key ecological engineering science and technology issues of "the spatial and temporal distribution characteristics and functions of tropical marine microbial diversity"

Lin Qiang

Ophiolite complexes represent the remnants of fossil oceanic lithosphere that formed in a range of tectonic settings. It is generally accepted that ophiolitic peridotites formed in fossil mid-oceanic ridge (MOR) and suprasubduction zone settings usually sample the upper 15–20 km of the oceanic lithospheric mantle (i.e. spinel/plagioclase-facies peridotite

Revealing Enzymatic Mechanism for Xanthone Formation in Marine Actinomycetes

Human Activity Increases Likelihood of More Extreme Heatwaves

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4th SYNGBIO

ZHANG Changsheng

Zhang Si

Lin Qiang